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HomoloGene:36436. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CISD2,  H.sapiens
CDGSH iron sulfur domain 2
NP_001008389.1
135 aa
CISD2,  P.troglodytes
CDGSH iron sulfur domain 2
XP_003310469.1
263 aa
LOC100429989,  M.mulatta
CDGSH iron sulfur domain-containing protein 2-like
XP_002804204.1
222 aa
CISD2,  B.taurus
CDGSH iron sulfur domain 2
NP_001073807.1
135 aa
Cisd2,  M.musculus
CDGSH iron sulfur domain 2
NP_080178.1
135 aa
Cisd2,  R.norvegicus
CDGSH iron sulfur domain 2
NP_001178537.1
135 aa
CISD2,  G.gallus
CDGSH iron sulfur domain 2
XP_420668.1
134 aa
cisd2,  X.tropicalis
CDGSH iron sulfur domain 2
NP_001011479.1
135 aa
cisd2,  D.rerio
CDGSH iron sulfur domain 2
NP_956677.1
135 aa
CG1458,  D.melanogaster
CG1458
NP_651684.1
133 aa
AgaP_AGAP004484,  A.gambiae
AgaP_AGAP004484
XP_313782.3
132 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Wolfram syndrome 2.



Publications
Articles associated with genes and sequences of this homology group.

Wolfram syndrome: phenotype and novel mutation in two Taiwanese siblings.
Shu SG, et al. J Formos Med Assoc 102, 808-11 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MitoNEET_N (pfam10660)
  Iron-containing outer mitochondrial membrane protein N-terminus.
zf-CDGSH (cl02748)
  Iron-binding zinc finger CDGSH type.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cisd2 includes H.sapiens CISD2 and R.norvegicus Cisd2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 13 species)
Actinopterygii - bony fishes (10 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (16 transcripts, 13 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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