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HomoloGene:38194. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TFPI2,  H.sapiens
tissue factor pathway inhibitor 2
NP_006519.1
235 aa
TFPI2,  P.troglodytes
tissue factor pathway inhibitor 2
XP_001168275.1
235 aa
TFPI2,  M.mulatta
tissue factor pathway inhibitor 2
XP_001099023.1
235 aa
TFPI2,  C.lupus
tissue factor pathway inhibitor 2
XP_532462.3
235 aa
TFPI2,  B.taurus
tissue factor pathway inhibitor 2
NP_877589.1
234 aa
Tfpi2,  M.musculus
tissue factor pathway inhibitor 2
NP_033390.1
230 aa
Tfpi2,  R.norvegicus
tissue factor pathway inhibitor 2
NP_775164.1
230 aa
TFPI2,  G.gallus
tissue factor pathway inhibitor 2
XP_418662.2
238 aa
tfpi2,  X.tropicalis
tissue factor pathway inhibitor 2
NP_001015766.1
219 aa
tfpi2,  D.rerio
tissue factor pathway inhibitor 2
NP_001035185.1
233 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Associations between TFPI-2 methylation and poor prognosis in glioblastomas.
VaitkienÄ— P, et al. Medicina (Kaunas) 48, 345-9 (2012).
Detection of TFPI2 methylation in the serum of gastric cancer patients.
Hibi K, et al. Anticancer Res 31, 3835-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Kunitz_BPTI (pfam00014)
  Kunitz/Bovine pancreatic trypsin inhibitor domain.
KU (cl00101)
  BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tfpi2 includes H.sapiens TFPI2 and R.norvegicus Tfpi2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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