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HomoloGene:55890. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HRAS,  H.sapiens
Harvey rat sarcoma viral oncogene homolog
NP_005334.1
189 aa
HRAS,  P.troglodytes
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
XP_521702.2
189 aa
HRAS,  M.mulatta
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
XP_001085804.1
189 aa
HRAS,  C.lupus
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
XP_540523.3
189 aa
HRAS,  B.taurus
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
NP_001229275.1
189 aa
Hras,  M.musculus
Harvey rat sarcoma virus oncogene
NP_001123915.1
189 aa
Hras,  R.norvegicus
Harvey rat sarcoma virus oncogene
NP_001091711.1
189 aa
HRAS,  G.gallus
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
NP_990623.1
189 aa
hras,  X.tropicalis
Harvey rat sarcoma viral oncogene homolog
NP_001017003.1
189 aa
hrasb,  D.rerio
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
NP_001018465.1
189 aa
hrasa,  D.rerio
v-Ha-ras Harvey rat sarcoma viral oncogene homolog a
NP_001017623.1
189 aa
LOC100151000,  D.rerio
GTPase HRas-like
XP_001923439.1
189 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Bladder cancer, somatic.
Thyroid carcinoma, follicular, somatic.
Costello syndrome.



Publications
Articles associated with genes and sequences of this homology group.

H-Ras transfers from B to T cells via tunneling nanotubes.
Rainy N, et al. Cell Death Dis 4, e726 (2013).
4-Hydroxytamoxifen induces autophagic death through K-Ras degradation.
Kohli L, et al. Cancer Res 73, 4395-405 (2013).
NMR-based functional profiling of RASopathies and oncogenic RAS mutations.
Smith MJ, et al. Proc Natl Acad Sci U S A 110, 4574-9 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hras1 includes H.sapiens HRAS and R.norvegicus Hras.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 9 species)
Actinopterygii - bony fishes (14 transcripts, 8 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (4 transcripts, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

 

 

 

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