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HomoloGene:56394. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EGR1,  H.sapiens
early growth response 1
NP_001955.1
543 aa
EGR1,  P.troglodytes
early growth response 1
XP_517958.3
524 aa
EGR1,  M.mulatta
early growth response 1
XP_001107731.2
545 aa
EGR1,  C.lupus
early growth response 1
XP_851238.1
542 aa
EGR1,  B.taurus
early growth response 1
NP_001039340.1
540 aa
Egr1,  M.musculus
early growth response 1
NP_031939.1
533 aa
Egr1,  R.norvegicus
early growth response 1
NP_036683.1
508 aa
EGR1,  G.gallus
early growth response 1
NP_989467.2
510 aa
egr1,  X.tropicalis
early growth response 1
NP_001090830.1
499 aa
egr1,  D.rerio
early growth response 1
NP_571323.1
511 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Egr1 regulates lithium-induced transcription of the Period 2 (PER2) gene.
Kim SH, et al. Biochim Biophys Acta 1832, 1969-79 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF3432 (pfam11914)
  Domain of unknown function (DUF3432).
DUF3446 (pfam11928)
  Domain of unknown function (DUF3446).
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
DUF3446 (pfam11928)
  Domain of unknown function (DUF3446).
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Egr1 includes H.sapiens EGR1 and R.norvegicus Egr1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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