Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:75079. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ANO1,  H.sapiens
anoctamin 1, calcium activated chloride channel
NP_060513.5
986 aa
ANO1,  P.troglodytes
anoctamin 1, calcium activated chloride channel
XP_003313240.1
1015 aa
LOC708723,  M.mulatta
anoctamin-1-like
XP_002799504.1
1164 aa
ANO1,  C.lupus
anoctamin 1, calcium activated chloride channel
XP_854489.4
1059 aa
ANO1,  B.taurus
anoctamin 1, calcium activated chloride channel
NP_001179646.1
985 aa
Ano1,  M.musculus
anoctamin 1, calcium activated chloride channel
NP_848757.4
1017 aa
Ano1,  R.norvegicus
anoctamin 1, calcium activated chloride channel
NP_001101034.1
1040 aa
ANO1,  G.gallus
anoctamin 1, calcium activated chloride channel
XP_004941586.1
1020 aa
ano1,  X.tropicalis
anoctamin 1, calcium activated chloride channel
NP_001123799.1
979 aa
ano1,  D.rerio
anoctamin 1, calcium activated chloride channel
NP_001155062.1
925 aa
CG16718,  D.melanogaster
CG16718
NP_001262736.1
926 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.
Terashima H, et al. Proc Natl Acad Sci U S A 110, 19354-9 (2013).
Non-canonical translation start sites in the TMEM16A chloride channel.
Sondo E, et al. Biochim Biophys Acta 1838, 89-97 (2014).
TMEM16A alternative splicing coordination in breast cancer.
Ubby I, et al. Mol Cancer 12, 75 (2013).
DOG1 immunoreactivity in uterine leiomyosarcomas.
Sah SP & McCluggage WG. J Clin Pathol 66, 40-3 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Anoctamin (pfam04547)
  Calcium-activated chloride channel.
Anoctamin (pfam04547)
  Calcium-activated chloride channel.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ano1 includes H.sapiens ANO1 and R.norvegicus Tmem16a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 7 species)
Mammalia - mammals (8 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 7 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

Support Center