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HomoloGene:10005. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

THAP1,  H.sapiens
THAP domain containing, apoptosis associated protein 1
NP_060575.1
213 aa
THAP1,  P.troglodytes
THAP domain containing, apoptosis associated protein 1
XP_528123.1
213 aa
THAP1,  M.mulatta
THAP domain containing, apoptosis associated protein 1
XP_001099355.1
212 aa
THAP1,  C.lupus
THAP domain containing, apoptosis associated protein 1
XP_848435.1
213 aa
THAP1,  B.taurus
THAP domain containing, apoptosis associated protein 1
NP_001029820.1
213 aa
Thap1,  M.musculus
THAP domain containing, apoptosis associated protein 1
NP_950243.1
210 aa
Thap1,  R.norvegicus
THAP domain containing, apoptosis associated protein 1
NP_001008341.1
210 aa
THAP1,  G.gallus
THAP domain containing, apoptosis associated protein 1
XP_004949398.1
244 aa
thap1,  X.tropicalis
THAP domain containing, apoptosis associated protein 1
NP_001006738.1
225 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dystonia 6, torsion.



Publications
Articles associated with genes and sequences of this homology group.

THAP1 mutations in a Greek primary blepharospasm series.
Xiromerisiou G, et al. Parkinsonism Relat Disord 19, 404-5 (2013).
THAP1 mutations and dystonia phenotypes: genotype phenotype correlations.
Xiromerisiou G, et al. Mov Disord 27, 1290-4 (2012).
Identification and functional analysis of novel THAP1 mutations.
Lohmann K, et al. Eur J Hum Genet 20, 171-5 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
THAP (cl02739)
  THAP domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Thap1 includes H.sapiens THAP1 and R.norvegicus Thap1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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