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HomoloGene:55800. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FASN,  H.sapiens
fatty acid synthase
NP_004095.4
2511 aa
FASN,  P.troglodytes
fatty acid synthase
XP_511758.2
2502 aa
FASN,  M.mulatta
fatty acid synthase
XP_001113076.1
2516 aa
FASN,  C.lupus
fatty acid synthase
XP_005624202.1
2475 aa
FASN,  B.taurus
fatty acid synthase
NP_001012687.1
2513 aa
Fasn,  M.musculus
fatty acid synthase
NP_032014.3
2504 aa
Fasn,  R.norvegicus
fatty acid synthase
NP_059028.1
2505 aa
FASN,  G.gallus
fatty acid synthase
NP_990486.2
2512 aa
fasn,  X.tropicalis
fatty acid synthase
XP_002937357.2
2514 aa
v(2)k05816,  D.melanogaster
v(2)k05816
NP_647613.1
2409 aa
fasn-1,  C.elegans
fasn-1
NP_492417.2
2613 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKS_DH (smart00826)
  Dehydratase domain in polyketide synthase (PKS) enzymes.
PKS_ER (smart00829)
  Enoylreductase.
Thioesterase (pfam00975)
  Thioesterase domain.
Methyltransf_12 (pfam08242)
  Methyltransferase domain.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
Acyl_transf_1 (cl08282)
  Acyl transferase domain.
hot_dog (cl00509)
  The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
Acyl_transf_1 (cl08282)
  Acyl transferase domain.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
PP-binding (cl09936)
  Phosphopantetheine attachment site.
cond_enzymes (cl09938)
  Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the ...
AdoMet_MTases (cl17173)
  S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
Hydrolase_4 (cl19140)
  Putative lysophospholipase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fasn includes H.sapiens FASN.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (30 transcripts, 11 species)
Arachnida - arachnids (4 transcripts, 2 species)

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Ascidiacea - tunicates (5 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (4 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (5 transcripts, 1 species)
Eurotiomycetes - ascomycetes (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Liliopsida - monocots (1 transcript, 1 species)

 

 

 

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