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HomoloGene:4788. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FARS2,  H.sapiens
phenylalanyl-tRNA synthetase 2, mitochondrial
NP_006558.1
451 aa
FARS2,  P.troglodytes
phenylalanyl-tRNA synthetase 2, mitochondrial
NP_001233392.1
451 aa
FARS2,  C.lupus
phenylalanyl-tRNA synthetase 2, mitochondrial
XP_545326.3
452 aa
FARS2,  B.taurus
phenylalanyl-tRNA synthetase 2, mitochondrial
NP_001070273.1
446 aa
Fars2,  M.musculus
phenylalanine-tRNA synthetase 2 (mitochondrial)
NP_077236.1
451 aa
Fars2,  R.norvegicus
phenylalanyl-tRNA synthetase 2, mitochondrial
NP_001013157.1
472 aa
FARS2,  G.gallus
phenylalanyl-tRNA synthetase 2, mitochondrial
XP_426039.2
449 aa
fars2,  X.tropicalis
phenylalanyl-tRNA synthetase 2, mitochondrial
XP_002936470.2
464 aa
fars2,  D.rerio
phenylalanyl-tRNA synthetase 2, mitochondrial
NP_001099064.1
449 aa
Aats-phe,  D.melanogaster
Phenylalanyl-tRNA synthetase
NP_477283.1
453 aa
AgaP_AGAP012096,  A.gambiae
AgaP_AGAP012096
XP_320432.3
464 aa
fars-2,  C.elegans
fars-2
NP_507852.2
458 aa
MSF1,  S.cerevisiae
MSF1
NP_015372.2
469 aa
KLLA0B12177g,  K.lactis
KLLA0B12177g
XP_452072.1
462 aa
AGOS_ADL305C,  E.gossypii
AGOS_ADL305C
NP_983791.2
459 aa
SPCC736.03c,  S.pombe
SPCC736.03c
NP_587774.1
429 aa
MGG_03217,  M.oryzae
MGG_03217
XP_003716762.1
533 aa
NCU01512,  N.crassa
NCU01512
XP_956961.1
517 aa
AT3G58140,  A.thaliana
AT3G58140
NP_567061.1
429 aa
Os12g0533700,  O.sativa
Os12g0533700
NP_001066926.1
429 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Crystallization and X-ray analysis of human cytoplasmic phenylalanyl-tRNA synthetase.
Finarov I, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun 65, 93-7 (2009).
Purification, crystallization and preliminary X-ray characterization of a human mitochondrial phenylalanyl-tRNA synthetase.
Levin I, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun 63, 761-4 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
pheS_mito (TIGR00469)
  phenylalanyl-tRNA synthetase, mitochondrial.
class_II_aaRS-like_core (cl00268)
  Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it ...
FDX-ACB (cl08386)
  This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fars2 includes H.sapiens FARS2 and R.norvegicus Fars2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (38 transcripts, 29 species)
Liliopsida - monocots (10 transcripts, 9 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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