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HomoloGene:74409. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CDK2,  H.sapiens
cyclin-dependent kinase 2
NP_001789.2
298 aa
CDK2,  P.troglodytes
cyclin-dependent kinase 2
XP_003952210.1
346 aa
CDK2,  M.mulatta
cyclin-dependent kinase 2
XP_001113345.1
298 aa
CDK2,  C.lupus
cyclin-dependent kinase 2
XP_005625536.1
346 aa
CDK2,  B.taurus
cyclin-dependent kinase 2
NP_001014934.1
298 aa
Cdk2,  M.musculus
cyclin-dependent kinase 2
NP_904326.1
346 aa
Cdk2,  R.norvegicus
cyclin dependent kinase 2
NP_955795.1
298 aa
CDK2,  G.gallus
cyclin-dependent kinase 2
NP_001186786.1
298 aa
cdk2,  X.tropicalis
cyclin-dependent kinase 2
NP_001008136.1
297 aa
cdk2,  D.rerio
cyclin-dependent kinase 2
NP_998571.1
298 aa
cdc2c,  D.melanogaster
cdc2c
NP_732544.1
314 aa
AgaP_AGAP004579,  A.gambiae
AgaP_AGAP004579
XP_562342.4
309 aa
CDC28,  S.cerevisiae
CDC28
NP_009718.3
298 aa
KLLA0B09790g,  K.lactis
KLLA0B09790g
XP_451964.1
295 aa
AGOS_ADR058C,  E.gossypii
AGOS_ADR058C
NP_984154.1
295 aa
cdc2,  S.pombe
cdc2
NP_595629.1
297 aa
MGG_01362,  M.oryzae
MGG_01362
XP_003714294.1
320 aa
NCU09778,  N.crassa
NCU09778
XP_960117.1
328 aa
CDC2,  A.thaliana
CDC2
NP_566911.1
294 aa
Os03g0118400,  O.sativa
Os03g0118400
NP_001048772.1
294 aa
Os02g0123100,  O.sativa
Os02g0123100
NP_001045731.1
292 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

[Changes of protein expression in HepG2 cells with CDK2 RNA interference].
Shang J, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29, 359-63 (2013).
Cyclin-dependent kinase 2 controls peripheral immune tolerance.
Chunder N, et al. J Immunol 189, 5659-66 (2012).
Cdk1-dependent control of membrane-trafficking dynamics.
McCusker D, et al. Mol Biol Cell 23, 3336-47 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLN00009 (PLN00009)
  cyclin-dependent kinase A; Provisional.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cdk2 includes H.sapiens CDK2 and R.norvegicus Cdk2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (55 transcripts, 33 species)
Liliopsida - monocots (24 transcripts, 8 species)
Coniferopsida - conifers (4 transcripts, 3 species)
Isoetopsida - club-mosses (4 transcripts, 1 species)
Bryopsida - mosses (3 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (3 transcripts, 2 species)

Chordata
Mammalia - mammals (15 transcripts, 12 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (17 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (6 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (3 transcripts, 1 species)

Codonosigidae
Monosiga - choanoflagellates (3 transcripts, 1 species)

 

 

 

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