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HomoloGene:27. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FAS,  H.sapiens
Fas cell surface death receptor
NP_000034.1
335 aa
FAS,  P.troglodytes
Fas (TNF receptor superfamily, member 6)
XP_001139138.2
335 aa
FAS,  M.mulatta
Fas (TNF receptor superfamily, member 6)
NP_001028105.1
333 aa
FAS,  C.lupus
Fas cell surface death receptor
XP_005636707.1
315 aa
FAS,  B.taurus
Fas (TNF receptor superfamily, member 6)
NP_777087.1
323 aa
Fas,  M.musculus
Fas (TNF receptor superfamily member 6)
NP_032013.2
327 aa
Fas,  R.norvegicus
Fas cell surface death receptor
NP_631933.2
324 aa
FAS,  G.gallus
Fas (TNF receptor superfamily, member 6)
NP_001186416.1
339 aa
fas,  X.tropicalis
Fas cell surface death receptor
NP_001096199.1
320 aa
fas,  D.rerio
Fas (TNF receptor superfamily, member 6)
XP_690447.4
293 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Squamous cell carcinoma, burn scar-related, somatic.
Autoimmune lymphoproliferative syndrome.
Autoimmune lymphoproliferative syndrome, type IA.



Publications
Articles associated with genes and sequences of this homology group.

Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.
Wiedemann MS, et al. Am J Physiol Endocrinol Metab 305, E388-95 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Death_FAS_TNFRSF6 (cd08316)
  Death domain of FAS or TNF receptor superfamily member 6.
TNFR (cd00185)
  Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and ...
DD (cl14633)
  Death Domain Superfamily of protein-protein interaction domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fas includes H.sapiens FAS and R.norvegicus Fas.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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