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HomoloGene:4070. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

LMAN1,  H.sapiens
lectin, mannose-binding, 1
NP_005561.1
510 aa
LMAN1,  P.troglodytes
lectin, mannose-binding, 1
XP_001143039.1
510 aa
LMAN1,  M.mulatta
lectin, mannose-binding, 1
XP_001088053.1
510 aa
LMAN1,  C.lupus
lectin, mannose-binding, 1
XP_533390.2
518 aa
LMAN1,  B.taurus
lectin, mannose-binding, 1
NP_001092413.1
518 aa
Lman1,  M.musculus
lectin, mannose-binding, 1
NP_001165533.1
517 aa
Lman1,  R.norvegicus
lectin, mannose-binding, 1
NP_446338.1
517 aa
LMAN1,  G.gallus
lectin, mannose-binding, 1
NP_001026570.1
503 aa
lman1,  X.tropicalis
lectin, mannose-binding, 1
NP_001234922.1
511 aa
lman1,  D.rerio
lectin, mannose-binding, 1
XP_688661.4
503 aa
ergic53,  D.melanogaster
ergic53
NP_524776.1
512 aa
AgaP_AGAP005404,  A.gambiae
AgaP_AGAP005404
XP_315413.3
526 aa
ile-1,  C.elegans
ile-1
NP_492548.1
492 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Combined factor V and VIII deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Two new mutations at ERGIC-53 gene in a Turkish family.
Torun D, et al. Clin Appl Thromb Hemost 17, 248-50 (2011).
Live imaging of bidirectional traffic from the ERGIC.
Ben-Tekaya H, et al. J Cell Sci 118, 357-67 (2005).
The cargo receptor ERGIC-53 is a target of the unfolded protein response.
Nyfeler B, et al. Biochem Biophys Res Commun 304, 599-604 (2003).
Lectins and traffic in the secretory pathway.
Hauri H, et al. FEBS Lett 476, 32-7 (2000).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
HMG-box (cl00082)
  High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
lectin_L-type (cl14058)
  legume lectins.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lman1 includes H.sapiens LMAN1 and R.norvegicus Lman1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (14 transcripts, 11 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (13 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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