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HomoloGene:11743. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HDAC11,  H.sapiens
histone deacetylase 11
NP_079103.2
347 aa
HDAC11,  P.troglodytes
histone deacetylase 11
XP_530587.3
308 aa
HDAC11,  M.mulatta
histone deacetylase 11
XP_001082767.1
347 aa
HDAC11,  C.lupus
histone deacetylase 11
XP_005632164.1
319 aa
HDAC11,  B.taurus
histone deacetylase 11
NP_001095526.1
386 aa
Hdac11,  M.musculus
histone deacetylase 11
NP_659168.1
347 aa
Hdac11,  R.norvegicus
histone deacetylase 11
NP_001100080.2
347 aa
HDAC11,  G.gallus
histone deacetylase 11
NP_001264070.1
358 aa
hdac11,  D.rerio
histone deacetylase 11
NP_001002171.1
366 aa
HdacX,  D.melanogaster
Histone deacetylase X
NP_001247296.1
343 aa
AgaP_AGAP001736,  A.gambiae
AgaP_AGAP001736
XP_321350.5
361 aa
hda-11,  C.elegans
hda-11
NP_505699.3
334 aa
HDA2,  A.thaliana
HDA2
NP_568480.2
387 aa
Os06g0571100,  O.sativa
Os06g0571100
NP_001057914.1
352 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

HDAC11 is a novel drug target in carcinomas.
Deubzer HE, et al. Int J Cancer 132, 2200-8 (2013).
From immunity to tolerance through HDAC.
Georgopoulos K. Nat Immunol 10, 13-4 (2009).
The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men.
Yang XJ & Seto E. Nat Rev Mol Cell Biol 9, 206-18 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Arginase_HDAC (cl17011)
  Arginase-like and histone-like hydrolases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hdac11 includes H.sapiens HDAC11 and R.norvegicus Hdac11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (19 transcripts, 18 species)
Liliopsida - monocots (10 transcripts, 7 species)
Bryopsida - mosses (2 transcripts, 1 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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