Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:386. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PSEN2,  H.sapiens
presenilin 2
NP_000438.2
448 aa
PSEN2,  P.troglodytes
presenilin 2 (Alzheimer disease 4)
XP_003949755.1
481 aa
PSEN2,  M.mulatta
presenilin 2 (Alzheimer disease 4)
XP_002801954.1
448 aa
PSEN2,  C.lupus
presenilin 2 (Alzheimer disease 4)
XP_005622685.1
465 aa
PSEN2,  B.taurus
presenilin 2 (Alzheimer disease 4)
NP_776865.2
449 aa
Psen2,  M.musculus
presenilin 2
NP_001122077.1
448 aa
Psen2,  R.norvegicus
presenilin 2
NP_112349.2
448 aa
PSEN2,  G.gallus
presenilin 2 (Alzheimer disease 4)
NP_989633.1
451 aa
psen2,  X.tropicalis
presenilin 2 (Alzheimer disease 4)
NP_001017181.1
451 aa
psen2,  D.rerio
presenilin 2
NP_571589.2
441 aa
Psn,  D.melanogaster
Presenilin
NP_001137988.1
508 aa
AgaP_AGAP002957,  A.gambiae
AgaP_AGAP002957
XP_311942.4
523 aa
Os01g0276400,  O.sativa
Os01g0276400
NP_001042728.2
351 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cardiomyopathy, dilated, 1V.
Alzheimer disease-4.



Publications
Articles associated with genes and sequences of this homology group.

Presenilin-2 gene mutation presenting as Lewy body dementia?
Raciti L, et al. Neurol Sci 32, 533-4 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Peptidase_A22B (cl01342)
  Signal peptide peptidase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Psen2 includes H.sapiens PSEN2 and R.norvegicus Psen2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 13 species)
Actinopterygii - bony fishes (12 transcripts, 10 species)
Ascidiacea - tunicates (6 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Hyperoartia - vertebrates (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 1 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

Support Center