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HomoloGene:7318. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

FOXM1,  H.sapiens
forkhead box M1
801 aa
FOXM1,  P.troglodytes
forkhead box M1
748 aa
FOXM1,  M.mulatta
forkhead box M1
727 aa
FOXM1,  C.lupus
forkhead box M1
765 aa
FOXM1,  B.taurus
forkhead box M1
760 aa
Foxm1,  M.musculus
forkhead box M1
757 aa
Foxm1,  R.norvegicus
forkhead box M1
771 aa
FOXM1,  G.gallus
forkhead box M1
795 aa
foxm1,  X.tropicalis
forkhead box M1
754 aa
foxm1,  D.rerio
forkhead box M1
623 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Signaling of miRNAs-FOXM1 in cancer and potential targeted therapy.
Shi M, et al. Curr Drug Targets 14, 1192-202 (2013).
MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.
Gayle SS, et al. Curr Med Chem 20, 2486-99 (2013).
FOX(M1) news--it is cancer.
Halasi M & Gartel AL. Mol Cancer Ther 12, 245-54 (2013).
FOXM1 is an oncogenic mediator in Ewing Sarcoma.
Christensen L, et al. PLoS One 8, e54556 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Foxm1 includes H.sapiens FOXM1 and R.norvegicus Foxm1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (7 transcripts, 7 species)
Aves - birds (3 transcripts, 1 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)




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