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HomoloGene:7336. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GDF3,  H.sapiens
growth differentiation factor 3
NP_065685.1
364 aa
GDF3,  P.troglodytes
growth differentiation factor 3
XP_508988.2
364 aa
GDF3,  M.mulatta
growth differentiation factor 3
XP_001112644.1
364 aa
GDF3,  C.lupus
growth differentiation factor 3
XP_534896.1
365 aa
GDF3,  B.taurus
growth differentiation factor 3
XP_002687893.1
364 aa
Gdf3,  M.musculus
growth differentiation factor 3
NP_032134.2
366 aa
Gdf3,  R.norvegicus
growth differentiation factor 3
NP_001103141.1
366 aa
GDF3,  G.gallus
growth differentiation factor 3
NP_990542.1
373 aa
gdf3,  X.tropicalis
growth differentiation factor 3
NP_001007905.1
350 aa
gdf1,  X.tropicalis
growth differentiation factor 1
NP_001016819.1
361 aa
dvr1,  D.rerio
decapentaplegic and Vg-related 1
NP_571023.1
355 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Klippel-Feil syndrome 3, autosomal dominant.
Microphthalmia with coloboma 6.
Microphthalmia, isolated 7.



Publications
Articles associated with genes and sequences of this homology group.

GDF-3 is an adipogenic cytokine under high fat dietary condition.
Wang W, et al. Biochem Biophys Res Commun 321, 1024-31 (2004).
Expression of cVg1 mRNA during chicken embryonic development.
Somi S, et al. Anat Rec A Discov Mol Cell Evol Biol 273, 603-8 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TGFb_propeptide (pfam00688)
  TGF-beta propeptide.
TGFb_propeptide (pfam00688)
  TGF-beta propeptide.
TGF_beta (cl02510)
  Transforming growth factor beta like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gdf3 includes H.sapiens GDF3 and R.norvegicus Gdf3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

 

 

 

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