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HomoloGene:55682. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MAPK3,  H.sapiens
mitogen-activated protein kinase 3
NP_002737.2
379 aa
MAPK3,  P.troglodytes
mitogen-activated protein kinase 3
XP_510921.3
379 aa
MAPK3,  M.mulatta
mitogen-activated protein kinase 3-like
XP_002802489.1
430 aa
LOC479790,  C.lupus
mitogen-activated protein kinase 3-like
NP_001238964.1
380 aa
MAPK3,  B.taurus
mitogen-activated protein kinase 3
NP_001103488.1
362 aa
Mapk3,  M.musculus
mitogen-activated protein kinase 3
NP_036082.1
380 aa
Mapk3,  R.norvegicus
mitogen activated protein kinase 3
NP_059043.1
380 aa
mapk3,  D.rerio
mitogen-activated protein kinase 3
NP_958915.1
392 aa
FUS3,  S.cerevisiae
FUS3
NP_009537.1
353 aa
KLLA0E10539g,  K.lactis
KLLA0E10539g
XP_454426.1
371 aa
AGOS_AFR019W,  E.gossypii
AGOS_AFR019W
NP_985566.1
359 aa
spk1,  S.pombe
spk1
NP_594009.1
372 aa
MGG_09565,  M.oryzae
MGG_09565
XP_003712175.1
356 aa
NCU02393,  N.crassa
NCU02393
XP_959713.2
354 aa
MPK1,  A.thaliana
MPK1
NP_001031017.1
370 aa
MPK2,  A.thaliana
MPK2
NP_564746.1
376 aa
Os06g0699400,  O.sativa
Os06g0699400
NP_001058471.1
369 aa
Os02g0148100,  O.sativa
Os02g0148100
NP_001045889.1
370 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ERK1/2 pathway is activated in degenerated Rpe65-deficient mice.
Métrailler S, et al. Exp Eye Res 116, 86-95 (2013).
ERK1 regulates the hematopoietic stem cell niches.
Saulnier N, et al. PLoS One 7, e30788 (2012).
Role of ERK1/2 activation in microtubule stabilization and glucose transport in cardiomyocytes.
Asrih M, et al. Am J Physiol Endocrinol Metab 301, E836-43 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
AdoMet_MTases (cl17173)
  S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mapk3 includes H.sapiens MAPK3 and R.norvegicus Mapk3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (61 transcripts, 31 species)
Liliopsida - monocots (25 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Chordata
Mammalia - mammals (13 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (16 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (4 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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