Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:328. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

APOB,  H.sapiens
apolipoprotein B
NP_000375.2
4563 aa
APOB,  P.troglodytes
apolipoprotein B (including Ag(x) antigen)
XP_515323.2
4562 aa
APOB,  M.mulatta
apolipoprotein B (including Ag(x) antigen)
XP_001097500.1
4555 aa
APOB,  C.lupus
apolipoprotein B (including Ag(x) antigen)
XP_005630653.1
4587 aa
Apob,  M.musculus
apolipoprotein B
NP_033823.2
4505 aa
Apob,  R.norvegicus
apolipoprotein B
NP_062160.2
4506 aa
APOB,  G.gallus
apolipoprotein B (including Ag(x) antigen)
NP_001038098.1
4631 aa
apob,  X.tropicalis
apolipoprotein B
XP_002934538.2
4621 aa
apoba,  D.rerio
apolipoprotein Ba
XP_694827.5
4418 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypobetalipoproteinemia.
Hypobetalipoproteinemia, normotriglyceridemic.
Hypercholesterolemia, due to ligand-defective apo B.



Publications
Articles associated with genes and sequences of this homology group.

Molecular description of familial defective APOB-100 in Malaysia.
Al-Khateeb AR, et al. Biochem Genet 51, 811-23 (2013).
Assessment of apoB dyslipoproteinemia in Korean population.
Moon HW, et al. Clin Biochem 46, 1041-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ApoB100_C (pfam12491)
  Apolipoprotein B100 C terminal.
LPD_N (smart00638)
  Lipoprotein N-terminal Domain.
Vitellogenin_N (pfam01347)
  Lipoprotein amino terminal region.
DUF1081 (pfam06448)
  Domain of Unknown Function (DUF1081).
DUF1943 (pfam09172)
  Domain of unknown function (DUF1943).
AAA_13 (pfam13166)
  AAA domain.
SbcC (COG0419)
  ATPase involved in DNA repair [DNA replication, recombination, and repair].
DUF964 (cl01483)
  Protein of unknown function (DUF964).
DUF1081 (pfam06448)
  Domain of Unknown Function (DUF1081).
DUF1351 (pfam07083)
  Protein of unknown function (DUF1351).
DUF1943 (pfam09172)
  Domain of unknown function (DUF1943).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Apob includes H.sapiens APOB and R.norvegicus Apob.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 10 species)
Aves - birds (2 transcripts, 2 species)

 

 

 

Support Center