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HomoloGene:62693. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CHD3,  H.sapiens
chromodomain helicase DNA binding protein 3
NP_001005271.2
2059 aa
CHD3,  P.troglodytes
chromodomain helicase DNA binding protein 3
XP_512012.3
2058 aa
CHD3,  M.mulatta
chromodomain helicase DNA binding protein 3
XP_001111066.1
1981 aa
CHD3,  C.lupus
chromodomain helicase DNA binding protein 3
XP_536627.3
1999 aa
CHD3,  B.taurus
chromodomain helicase DNA binding protein 3
XP_003587462.2
2038 aa
Chd3,  M.musculus
chromodomain helicase DNA binding protein 3
NP_666131.3
2055 aa
Chd3,  R.norvegicus
chromodomain helicase DNA binding protein 3
XP_006246936.1
2101 aa
chd3,  X.tropicalis
chromodomain helicase DNA binding protein 3
XP_002940874.2
2036 aa
chd3,  D.rerio
chromodomain helicase DNA binding protein 3
XP_696641.3
2063 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

UV radiation regulates Mi-2 through protein translation and stability.
Burd CJ, et al. J Biol Chem 283, 34976-82 (2008).
Mi-2/NuRD: multiple complexes for many purposes.
Bowen NJ, et al. Biochim Biophys Acta 1677, 52-7 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CHDNT (pfam08073)
  CHDNT (NUC034) domain.
DUF1087 (pfam06465)
  Domain of Unknown Function (DUF1087).
PHA03418 (PHA03418)
  hypothetical E4 protein; Provisional.
PHD (pfam00628)
  PHD-finger.
SNF2_N (pfam00176)
  SNF2 family N-terminal domain.
DUF1086 (pfam06461)
  Domain of Unknown Function (DUF1086).
CHDCT2 (pfam08074)
  CHDCT2 (NUC038) domain.
HELICc (cd00079)
  Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
SNF2_N (pfam00176)
  SNF2 family N-terminal domain.
DUF1086 (pfam06461)
  Domain of Unknown Function (DUF1086).
DUF1087 (pfam06465)
  Domain of Unknown Function (DUF1087).
CHDNT (pfam08073)
  CHDNT (NUC034) domain.
CHDCT2 (pfam08074)
  CHDCT2 (NUC038) domain.
ZipA (cl12038)
  ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic ...
PHD (cl17445)
  PHD-finger.
CHROMO (cl17459)
  Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence implicates the chromo domain in the binding activity of these proteins to methylated histone tails and maybe RNA. May occur as single instance, in a tandem arrangement or followd by a related "chromo shadow" domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chd3 includes H.sapiens CHD3 and R.norvegicus Chd3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (25 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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