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HomoloGene:11827. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EDC3,  H.sapiens
enhancer of mRNA decapping 3
NP_001135915.1
508 aa
EDC3,  P.troglodytes
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
XP_003952756.1
446 aa
EDC3,  M.mulatta
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
XP_002804909.1
508 aa
EDC3,  C.lupus
enhancer of mRNA decapping 3
XP_005638679.1
508 aa
EDC3,  B.taurus
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
NP_001026928.1
266 aa
Edc3,  M.musculus
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
NP_722494.1
508 aa
Edc3,  R.norvegicus
enhancer of mRNA decapping 3
XP_002729954.2
506 aa
EDC3,  G.gallus
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
NP_001025556.1
506 aa
edc3,  X.tropicalis
enhancer of mRNA decapping 3
NP_001120062.1
505 aa
edc3,  D.rerio
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
NP_001018136.1
507 aa
Edc3,  D.melanogaster
Enhancer of decapping 3
NP_648992.1
680 aa
AgaP_AGAP003131,  A.gambiae
AgaP_AGAP003131
XP_312817.4
549 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Crystal structure of human Edc3 and its functional implications.
Ling SH, et al. Mol Cell Biol 28, 5965-76 (2008).
A divergent Sm fold in EDC3 proteins mediates DCP1 binding and P-body targeting.
Tritschler F, et al. Mol Cell Biol 27, 8600-11 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
YjeF_N (pfam03853)
  YjeF-related protein N-terminus.
FDF (pfam09532)
  FDF domain.
YjeF_N (cl00318)
  YjeF-related protein N-terminus.
FDF (pfam09532)
  FDF domain.
Sm_like (cl00259)
  Sm and related proteins.
YjeF_N (cl00318)
  YjeF-related protein N-terminus.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Edc3 includes H.sapiens EDC3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 4 species)

 

 

 

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