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HomoloGene:3066. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PYY,  H.sapiens
peptide YY
NP_004151.3
97 aa
PYY,  P.troglodytes
peptide YY
XP_523780.3
97 aa
PYY,  M.mulatta
peptide YY
XP_001113958.1
97 aa
PYY,  C.lupus
peptide YY
XP_005624470.1
97 aa
PYY,  B.taurus
peptide YY
NP_001035677.1
97 aa
Pyy,  M.musculus
peptide YY
NP_663410.1
98 aa
Pyy,  R.norvegicus
peptide YY (mapped)
NP_001029252.1
98 aa
pyy,  X.tropicalis
peptide YY
NP_001072427.1
99 aa
pyya,  D.rerio
peptide YYa
NP_001157843.1
97 aa
pyyb,  D.rerio
peptide YYb
XP_001333222.2
95 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Obesity.



Publications
Articles associated with genes and sequences of this homology group.

Role of peptide YY(3-36) in the satiety produced by gastric delivery of macronutrients in rats.
Reidelberger R, et al. Am J Physiol Endocrinol Metab 304, E944-50 (2013).
The role of peptide YY in gastrointestinal diseases and disorders (review).
El-Salhy M, et al. Int J Mol Med 31, 275-82 (2013).
Case of peptide-YY-producing strumal carcinoid of the ovary: a case report and review.
Takatori E, et al. J Obstet Gynaecol Res 38, 1266-70 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PAH (cl00111)
  Pancreatic Hormone domain, a regulator of pancreatic and gastrointestinal functions; neuropeptide Y (NPY)b, peptide YY (PYY), and pancreatic polypetide (PP) are closely related; propeptide is enzymatically cleaved to yield the mature active peptide with amidated C-terminal ends; receptor binding and activation functions may reside in the N- and C-termini respectively; occurs in neurons, intestinal endocrine cells, and pancreas; exist as monomers and dimers



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pyy includes H.sapiens PYY and R.norvegicus Pyy.

 

 

 

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