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HomoloGene:2475. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NR2C2,  H.sapiens
nuclear receptor subfamily 2, group C, member 2
NP_003289.2
615 aa
NR2C2,  P.troglodytes
nuclear receptor subfamily 2, group C, member 2
XP_001158643.1
615 aa
NR2C2,  M.mulatta
nuclear receptor subfamily 2, group C, member 2
XP_002798750.1
648 aa
NR2C2,  C.lupus
nuclear receptor subfamily 2, group C, member 2
XP_005632175.1
629 aa
NR2C2,  B.taurus
nuclear receptor subfamily 2, group C, member 2
NP_001178990.1
611 aa
Nr2c2,  M.musculus
nuclear receptor subfamily 2, group C, member 2
NP_035760.1
596 aa
Nr2c2,  R.norvegicus
nuclear receptor subfamily 2, group C, member 2
NP_059019.1
596 aa
NR2C2,  G.gallus
nuclear receptor subfamily 2, group C, member 2
XP_004944782.1
629 aa
nr2c2,  X.tropicalis
nuclear receptor subfamily 2, group C, member 2
XP_002938282.2
595 aa
nr2c2,  D.rerio
nuclear receptor subfamily 2, group C, member 2
NP_001116766.1
623 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

TAK1 ubiquitination regulates doxorubicin-induced NF-κB activation.
Liang L, et al. Cell Signal 25, 247-54 (2013).
Premature aging with impaired oxidative stress defense in mice lacking TR4.
Lee YF, et al. Am J Physiol Endocrinol Metab 301, E91-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr2c2 includes H.sapiens NR2C2 and R.norvegicus Nr2c2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (7 transcripts, 5 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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