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HomoloGene:7734. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

GJD2,  H.sapiens
gap junction protein, delta 2, 36kDa
321 aa
GJD2,  P.troglodytes
gap junction protein, delta 2, 36kDa
321 aa
GJD2,  C.lupus
gap junction protein, delta 2, 36kDa
321 aa
GJD2,  B.taurus
gap junction protein, delta 2, 36kDa
321 aa
Gjd2,  M.musculus
gap junction protein, delta 2
321 aa
Gjd2,  R.norvegicus
gap junction protein, delta 2
321 aa
GJD2,  G.gallus
gap junction protein, delta 2, 36kDa
304 aa
gjd2,  X.tropicalis
gap junction protein, delta 2, 36kDa
304 aa
cx35b,  D.rerio
connexin 35b
304 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Connexin 36 mediates blood cell flow in mouse pancreatic islets.
Short KW, et al. Am J Physiol Endocrinol Metab 306, E324-31 (2014).
Estimating functional connectivity in an electrically coupled interneuron network.
Alcami P & Marty A. Proc Natl Acad Sci U S A 110, E4798-807 (2013).
Regulation of interneuron excitability by gap junction coupling with principal cells.
Apostolides PF & Trussell LO. Nat Neurosci 16, 1764-72 (2013).
Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice.
Carvalho CP, et al. Am J Physiol Endocrinol Metab 303, E144-51 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Connexin (cl02435)
Connexin_CCC (cl11207)
  Gap junction channel protein cysteine-rich domain.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gjd2 includes H.sapiens GJD2 and R.norvegicus Gjd2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (6 transcripts, 5 species)
Mammalia - mammals (5 transcripts, 5 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)




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