Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:121574. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PRKACA,  H.sapiens
protein kinase, cAMP-dependent, catalytic, alpha
NP_002721.1
351 aa
PRKACA,  P.troglodytes
protein kinase, cAMP-dependent, catalytic, alpha
XP_001171437.1
427 aa
PRKACA,  C.lupus
protein kinase, cAMP-dependent, catalytic, alpha
NP_001003032.1
350 aa
PRKACA,  B.taurus
protein kinase, cAMP-dependent, catalytic, alpha
NP_777009.1
351 aa
Prkaca,  M.musculus
protein kinase, cAMP dependent, catalytic, alpha
NP_032880.1
351 aa
Prkaca,  R.norvegicus
protein kinase, cAMP-dependent, catalytic, alpha
NP_001094392.1
351 aa
prkaca,  X.tropicalis
protein kinase, cAMP-dependent, catalytic, alpha
NP_001016403.1
351 aa
prkacab,  D.rerio
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
NP_001003470.1
351 aa
TPK2,  S.cerevisiae
TPK2
NP_015121.1
380 aa
KLLA0D03190g,  K.lactis
KLLA0D03190g
XP_453207.1
372 aa
AGOS_AFL090W,  E.gossypii
AGOS_AFL090W
NP_985458.1
346 aa
pka1,  S.pombe
pka1
NP_595159.1
512 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome.
Beuschlein F, et al. N Engl J Med 370, 1019-28 (2014).
PKA controls calcium influx into motor neurons during a rhythmic behavior.
Wang H & Sieburth D. PLoS Genet 9, e1003831 (2013).
Probes of the mitochondrial cAMP-dependent protein kinase.
Shell JR & Lawrence DS. Biochim Biophys Acta 1834, 1359-63 (2013).
Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity.
Kovalevsky AY, et al. Acta Crystallogr D Biol Crystallogr 68, 854-60 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkaca includes H.sapiens PRKACA and R.norvegicus Prkaca.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)

Arthropoda
Insecta - insects (5 transcripts, 3 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 1 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (4 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (10 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)

 

 

 

Support Center