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HomoloGene:36328. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

MYO10,  H.sapiens
myosin X
2058 aa
MYO10,  P.troglodytes
myosin X
2058 aa
MYO10,  C.lupus
myosin X
2050 aa
MYO10,  B.taurus
myosin X
2052 aa
Myo10,  M.musculus
myosin X
2062 aa
Myo10,  R.norvegicus
myosin X
1748 aa
MYO10,  G.gallus
myosin X
2078 aa
myo10,  D.rerio
myosin X
2069 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Cloning, characterization, and promoter analysis of mouse Myo10 gene.
Lai M, et al. Nucleosides Nucleotides Nucleic Acids 32, 354-65 (2013).
Myosin-X functions in polarized epithelial cells.
Liu KC, et al. Mol Biol Cell 23, 1675-87 (2012).
Phospholipid-dependent regulation of the motor activity of myosin X.
Umeki N, et al. Nat Struct Mol Biol 18, 783-8 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Trichoplein (pfam13868)
  Tumour suppressor, Mitostatin.
PH-like (cl00273)
  Pleckstrin homology-like domain.
IQ (cl15479)
  IQ calmodulin-binding motif.
B41 (smart00295)
  Band 4.1 homologues.
FERM_M (pfam00373)
  FERM central domain.
UBQ (cl00155)
  Ubiquitin-like proteins.
MyTH4 (cl02480)
  MyTH4 domain.
PH-like (cl17171)
  Pleckstrin homology-like domain.
FERM_M (pfam00373)
  FERM central domain.
UBQ (cl00155)
  Ubiquitin-like proteins.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
MyTH4 (cl02480)
  MyTH4 domain.
IQ (cl15479)
  Calmodulin-binding motif.
PH-like (cl17171)
  Pleckstrin homology-like domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myo10 includes H.sapiens MYO10 and R.norvegicus Myo10.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (19 transcripts, 7 species)
Mammalia - mammals (18 transcripts, 12 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Anthozoa - anthozoans (1 transcript, 1 species)

Echinoidea - sea urchins (1 transcript, 1 species)

Monosiga - choanoflagellates (1 transcript, 1 species)




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