Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:129366. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CTSL,  H.sapiens
cathepsin L
NP_001903.1
333 aa
CTSL1,  P.troglodytes
cathepsin L1
XP_003951515.1
333 aa
CTSL,  M.mulatta
cathepsin L1-like
XP_001086247.1
333 aa
CTSL1,  B.taurus
cathepsin L1
NP_001077155.1
333 aa
AT5G50260,  A.thaliana
AT5G50260
NP_568722.1
361 aa
AT3G48350,  A.thaliana
AT3G48350
NP_566901.1
364 aa
AT3G48340,  A.thaliana
AT3G48340
NP_680113.3
361 aa
Os08g0556900,  O.sativa
Os08g0556900
NP_001062479.1
385 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cathepsin L is highly expressed in gastrointestinal stromal tumors.
Miyamoto K, et al. Int J Oncol 39, 1109-15 (2011).
Epigenetic regulation of cathepsin L expression in chronic myeloid leukaemia.
Samaiya M, et al. J Cell Mol Med 15, 2189-99 (2011).
Post-transcriptional regulation of human cathepsin L expression.
Mittal S, et al. Biol Chem 392, 405-13 (2011).
[Relationship between cathepsin L and invasion and metastasis of ovarian carcinoma cells].
Wang SM, et al. Zhonghua Fu Chan Ke Za Zhi 45, 598-602 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Peptidase_C1 (cl00298)
  C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some ...
Inhibitor_I29 (cl07031)
  Cathepsin propeptide inhibitor domain (I29).



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (58 transcripts, 29 species)
Liliopsida - monocots (22 transcripts, 8 species)
Coniferopsida - conifers (9 transcripts, 3 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 1 species)

 

 

 

Support Center