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HomoloGene:56879. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FAM20C,  H.sapiens
family with sequence similarity 20, member C
NP_064608.2
584 aa
LOC740357,  P.troglodytes
extracellular serine/threonine protein kinase Fam20C-like
XP_001142331.2
336 aa
FAM20C,  M.mulatta
family with sequence similarity 20, member C
XP_001083623.1
584 aa
FAM20C,  C.lupus
family with sequence similarity 20, member C
XP_005621279.1
582 aa
FAM20C,  B.taurus
family with sequence similarity 20, member C
XP_002698221.1
548 aa
Fam20c,  M.musculus
family with sequence similarity 20, member C
NP_085042.2
579 aa
Fam20c,  R.norvegicus
family with sequence similarity 20, member C
NP_001012238.1
579 aa
FAM20C,  G.gallus
family with sequence similarity 20, member C
XP_414753.4
506 aa
LOC100498448,  X.tropicalis
extracellular serine/threonine protein kinase FAM20C-like
XP_002931990.1
575 aa
LOC792520,  D.rerio
extracellular serine/threonine protein kinase FAM20C-like
XP_001332042.4
559 aa
fam20cb,  D.rerio
family with sequence similarity 20, member Cb
XP_688892.5
557 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Raine syndrome.



Publications
Articles associated with genes and sequences of this homology group.

The specific role of FAM20C in amelogenesis.
Wang X, et al. J Dent Res 92, 995-9 (2013).
FAM20C plays an essential role in the formation of murine teeth.
Wang X, et al. J Biol Chem 287, 35934-42 (2012).
Osteosclerotic bone dysplasia in siblings with a Fam20C mutation.
Fradin M, et al. Clin Genet 80, 177-83 (2011).
Expression of FAM20C in the osteogenesis and odontogenesis of mouse.
Wang X, et al. J Histochem Cytochem 58, 957-67 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FAM20_C_like (cl05973)
  C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins.
FAM20_C_like (cl05973)
  C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fam20c includes H.sapiens FAM20C and R.norvegicus Fam20c.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (11 transcripts, 6 species)
Mammalia - mammals (10 transcripts, 10 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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