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HomoloGene:20350. Gene conserved in Amniota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CX3CR1,  H.sapiens
chemokine (C-X3-C motif) receptor 1
NP_001328.1
355 aa
CX3CR1,  P.troglodytes
chemokine (C-X3-C motif) receptor 1
NP_001139725.1
355 aa
CX3CR1,  M.mulatta
chemokine (C-X3-C motif) receptor 1
XP_001084169.1
355 aa
CX3CR1,  C.lupus
chemokine (C-X3-C motif) receptor 1
XP_005634322.1
356 aa
CX3CR1,  B.taurus
chemokine (C-X3-C motif) receptor 1
NP_001096028.1
358 aa
Cx3cr1,  M.musculus
chemokine (C-X3-C motif) receptor 1
NP_034117.3
354 aa
Cx3cr1,  R.norvegicus
chemokine (C-X3-C motif) receptor 1
NP_598218.1
354 aa
CX3CR1,  G.gallus
chemokine (C-X3-C motif) receptor 1
XP_004939539.1
354 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Rapid progression to AIDS from HIV1 infection.



Publications
Articles associated with genes and sequences of this homology group.

Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression.
Hochheiser K, et al. J Clin Invest 123, 4242-54 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHA02834 (PHA02834)
  chemokine receptor-like protein; Provisional.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
PHA03087 (PHA03087)
  G protein-coupled chemokine receptor-like protein; Provisional.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cx3cr1 includes H.sapiens CX3CR1 and R.norvegicus Cx3cr1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)

 

 

 

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