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HomoloGene:371. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PAFAH1B1,  H.sapiens
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
NP_000421.1
410 aa
PAFAH1B1,  P.troglodytes
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
NP_001029263.1
410 aa
PAFAH1B1,  M.mulatta
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
XP_001087675.1
410 aa
PAFAH1B1,  C.lupus
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
XP_854482.1
410 aa
PAFAH1B1,  B.taurus
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
NP_777088.1
410 aa
Pafah1b1,  M.musculus
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
NP_038653.1
410 aa
Pafah1b1,  R.norvegicus
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1
NP_113951.1
410 aa
PAFAH1B1,  G.gallus
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
NP_989655.1
410 aa
pafah1b1,  X.tropicalis
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
NP_991399.1
410 aa
pafah1b1a,  D.rerio
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a
NP_958502.1
410 aa
lis-1,  C.elegans
lis-1
NP_499755.1
404 aa
MGG_09369,  M.oryzae
MGG_09369
XP_003720251.1
461 aa
NCU04534,  N.crassa
NCU04534
XP_956945.2
451 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Miller-Dieker lissencephaly syndrome.
Subcortical laminar heterotopia.
Lissencephaly-1.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
WD40 (cd00200)
  WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pafah1b1 includes H.sapiens PAFAH1B1 and R.norvegicus Pafah1b1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (25 transcripts, 11 species)
Mammalia - mammals (17 transcripts, 16 species)
Aves - birds (3 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (12 transcripts, 10 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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