Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:4584. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TSG101,  H.sapiens
tumor susceptibility 101
NP_006283.1
390 aa
TSG101,  P.troglodytes
tumor susceptibility gene 101
XP_001173373.1
390 aa
TSG101,  C.lupus
tumor susceptibility 101
XP_542525.1
391 aa
TSG101,  B.taurus
tumor susceptibility gene 101
NP_001091464.1
391 aa
Tsg101,  M.musculus
tumor susceptibility gene 101
NP_068684.1
391 aa
Tsg101,  R.norvegicus
tumor susceptibility 101
NP_853659.2
391 aa
TSG101,  G.gallus
tumor susceptibility gene 101
NP_001264344.1
390 aa
tsg101,  X.tropicalis
tumor susceptibility gene 101
NP_989266.1
395 aa
tsg101a,  D.rerio
tumor susceptibility gene 101a
NP_001002089.1
390 aa
TSG101,  D.melanogaster
tumor suppressor protein 101
NP_524120.1
408 aa
AgaP_AGAP005934,  A.gambiae
AgaP_AGAP005934
XP_315964.4
395 aa
tsg-101,  C.elegans
tsg-101
NP_500364.2
425 aa
MGG_04712,  M.oryzae
MGG_04712
XP_003710824.1
581 aa
ELC,  A.thaliana
ELC
NP_566423.1
398 aa
ELC-Like,  A.thaliana
ELC-Like
NP_196890.1
368 aa
Os02g0833300,  O.sativa
Os02g0833300
NP_001048634.1
402 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Breast cancer.



Publications
Articles associated with genes and sequences of this homology group.

[Expression and significance of tumor susceptibility gene 101 in hepatocellular carcinoma tissues].
Gu RJ, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28, 738-40 (2012).
Analysis of expression and structure of the TSG101 gene in cervical cancer cells.
Broniarczyk J, et al. Int J Mol Med 25, 777-83 (2010).
Genetic analysis of ESCRT function in Drosophila: a tumour model for human Tsg101.
Herz HM & Bergmann A. Biochem Soc Trans 37, 204-7 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Vps23_core (pfam09454)
  Vps23 core domain.
DUF1640 (pfam07798)
  Protein of unknown function (DUF1640).
UEV (pfam05743)
  UEV domain.
TMF_DNA_bd (pfam12329)
  TATA element modulatory factor 1 DNA binding.
SynN (cl00143)
  Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
DAZAP2 (pfam11029)
  DAZ associated protein 2 (DAZAP2).
GrpE (cl03075)
  GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding. ...
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tsg101 includes H.sapiens TSG101 and R.norvegicus Tsg101.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 15 species)
Actinopterygii - bony fishes (17 transcripts, 10 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (12 transcripts, 12 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (29 transcripts, 21 species)
Liliopsida - monocots (7 transcripts, 7 species)
Coniferopsida - conifers (4 transcripts, 3 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

 

 

 

Support Center