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HomoloGene:20215. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DRD4,  H.sapiens
dopamine receptor D4
NP_000788.2
419 aa
DRD4,  M.mulatta
dopamine receptor D4
XP_001087197.1
428 aa
Drd4,  M.musculus
dopamine receptor D4
NP_031904.1
387 aa
Drd4,  R.norvegicus
dopamine receptor D4
NP_037076.1
385 aa
DRD4,  G.gallus
dopamine receptor D4
NP_001136321.1
378 aa
drd4,  X.tropicalis
dopamine receptor D4
XP_002937535.2
414 aa
drd4b,  D.rerio
dopamine receptor D4b
NP_001012636.1
382 aa
drd4a,  D.rerio
dopamine receptor D4a
NP_001012634.1
375 aa
GPRDOP3,  A.gambiae
GPRDOP3
XP_003436820.1
466 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Autonomic nervous system dysfunction.
Attention deficit-hyperactivity disorder.
Parkinson disease, protection against.
Novelty seeking personality.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7TM_GPCR_Srsx (pfam10320)
  Serpentine type 7TM GPCR chemoreceptor Srsx.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Drd4 includes H.sapiens DRD4 and R.norvegicus Drd4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (7 transcripts, 4 species)
Mammalia - mammals (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

 

 

 

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