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HomoloGene:20190. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CHRM2,  H.sapiens
cholinergic receptor, muscarinic 2
NP_001006631.1
466 aa
CHRM2,  P.troglodytes
cholinergic receptor, muscarinic 2
XP_001147308.1
466 aa
CHRM2,  C.lupus
cholinergic receptor, muscarinic 2
XP_005629635.1
466 aa
CHRM2,  B.taurus
cholinergic receptor, muscarinic 2
NP_001074202.1
465 aa
Chrm2,  M.musculus
cholinergic receptor, muscarinic 2, cardiac
NP_987076.2
466 aa
LOC102551851,  R.norvegicus
muscarinic acetylcholine receptor M2-like
XP_006236398.1
466 aa
CHRM2,  G.gallus
cholinergic receptor, muscarinic 2
NP_001025936.1
466 aa
chrm2,  X.tropicalis
cholinergic receptor, muscarinic 2
XP_002942846.1
470 aa
chrm2a,  D.rerio
cholinergic receptor, muscarinic 2a
NP_840086.1
495 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Activation and dynamic network of the M2 muscarinic receptor.
Miao Y, et al. Proc Natl Acad Sci U S A 110, 10982-7 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
SRP-alpha_N (pfam04086)
  Signal recognition particle, alpha subunit, N-terminal.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
S100PBPR (pfam15427)
  S100P-binding protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chrm2 includes H.sapiens CHRM2 and R.norvegicus Chrm2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 5 species)
Aves - birds (2 transcripts, 1 species)

 

 

 

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