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HomoloGene:31124. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SKI,  H.sapiens
v-ski avian sarcoma viral oncogene homolog
NP_003027.1
728 aa
SKI,  M.mulatta
v-ski sarcoma viral oncogene homolog (avian)
XP_001086434.1
970 aa
SKI,  C.lupus
v-ski avian sarcoma viral oncogene homolog
XP_005620652.1
867 aa
SKI,  B.taurus
v-ski sarcoma viral oncogene homolog (avian)
XP_002694226.2
800 aa
Ski,  M.musculus
ski sarcoma viral oncogene homolog (avian)
NP_035515.2
727 aa
Ski,  R.norvegicus
v-ski avian sarcoma viral oncogene homolog
XP_006239683.1
790 aa
SKI,  G.gallus
v-ski sarcoma viral oncogene homolog
NP_001034407.1
750 aa
ski,  X.tropicalis
v-ski sarcoma viral oncogene homolog (avian)
XP_004916211.1
719 aa
skia,  D.rerio
nuclear oncoprotein skia
NP_571010.2
727 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
1p36 deletion syndrome.



Publications
Articles associated with genes and sequences of this homology group.

MicroRNA29a regulates the expression of the nuclear oncogene Ski.
Teichler S, et al. Blood 118, 1899-902 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ski_Sno (pfam02437)
  SKI/SNO/DAC family.
c-SKI_SMAD_bind (cl07406)
  c-SKI Smad4 binding domain.
DUF2058 (cl01201)
  Uncharacterized protein conserved in bacteria (DUF2058).
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
DUF4200 (pfam13863)
  Domain of unknown function (DUF4200).
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ski includes H.sapiens SKI.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 8 species)
Actinopterygii - bony fishes (8 transcripts, 5 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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