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HomoloGene:100680. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RPS6KA2,  H.sapiens
ribosomal protein S6 kinase, 90kDa, polypeptide 2
NP_066958.2
733 aa
RPS6KA2,  P.troglodytes
ribosomal protein S6 kinase, 90kDa, polypeptide 2
XP_003311634.1
755 aa
RPS6KA2,  C.lupus
ribosomal protein S6 kinase, 90kDa, polypeptide 2
XP_003432598.2
758 aa
RPS6KA2,  B.taurus
ribosomal protein S6 kinase, 90kDa, polypeptide 2
NP_001179407.1
733 aa
Rps6ka2,  M.musculus
ribosomal protein S6 kinase, polypeptide 2
NP_035429.1
733 aa
Rps6ka2,  R.norvegicus
ribosomal protein S6 kinase polypeptide 2
NP_476469.1
733 aa
RPS6KA2,  G.gallus
ribosomal protein S6 kinase, 90kDa, polypeptide 2
XP_419611.2
733 aa
rps6ka2,  X.tropicalis
ribosomal protein S6 kinase, 90kDa, polypeptide 2
XP_002942396.2
732 aa
rps6ka2,  D.rerio
ribosomal protein S6 kinase, 90kDa, polypeptide 2
XP_699952.2
733 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

p90 ribosomal S6 kinase 3 contributes to cardiac insufficiency in α-tropomyosin Glu180Gly transgenic mice.
Passariello CL, et al. Am J Physiol Heart Circ Physiol 305, H1010-9 (2013).
RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.
Serra V, et al. J Clin Invest 123, 2551-63 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rps6ka2 includes H.sapiens RPS6KA2 and R.norvegicus Rps6ka2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (16 transcripts, 6 species)
Mammalia - mammals (14 transcripts, 11 species)
Aves - birds (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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