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HomoloGene:74509. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ABCB11,  H.sapiens
ATP-binding cassette, sub-family B (MDR/TAP), member 11
NP_003733.2
1321 aa
ABCB11,  P.troglodytes
ATP-binding cassette, sub-family B (MDR/TAP), member 11
XP_526100.2
1321 aa
ABCB11,  M.mulatta
ATP-binding cassette, sub-family B (MDR/TAP), member 11
XP_001097771.2
1225 aa
ABCB11,  C.lupus
ATP-binding cassette, sub-family B (MDR/TAP), member 11
NP_001137404.1
1325 aa
ABCB11,  B.taurus
ATP-binding cassette, sub-family B (MDR/TAP), member 11
NP_001179632.1
1324 aa
Abcb11,  M.musculus
ATP-binding cassette, sub-family B (MDR/TAP), member 11
NP_066302.2
1321 aa
Abcb11,  R.norvegicus
ATP-binding cassette, subfamily B (MDR/TAP), member 11
NP_113948.1
1321 aa
ABCB11,  G.gallus
ATP-binding cassette, sub-family B (MDR/TAP), member 11
XP_004942815.1
1347 aa
LOC100489579,  X.tropicalis
bile salt export pump-like
XP_004917764.1
1349 aa
abcb11b,  D.rerio
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
XP_003199513.2
1348 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cholestasis, progressive familial intrahepatic 2.



Publications
Articles associated with genes and sequences of this homology group.

Bile salt export pump (BSEP/ABCB11): trafficking and sorting disturbances.
Hayashi H & Sugiyama Y. Curr Mol Pharmacol 6, 95-103 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_membrane (pfam00664)
  ABC transporter transmembrane region.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abcb11 includes H.sapiens ABCB11 and R.norvegicus Abcb11.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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