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HomoloGene:333. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CDKN1A,  H.sapiens
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
164 aa
CDKN1A,  P.troglodytes
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
164 aa
CDKN1A,  M.mulatta
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
164 aa
CDKN1A,  C.lupus
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
164 aa
CDKN1A,  B.taurus
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
161 aa
Cdkn1a,  M.musculus
cyclin-dependent kinase inhibitor 1A (P21)
159 aa
Cdkn1a,  R.norvegicus
cyclin-dependent kinase inhibitor 1A
164 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Cdkn1a is a key mediator of rat pancreatic stellate cell senescence.
Fitzner B, et al. Pancreatology 13, 254-62 (2013).
The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD.
Chiappara G, et al. Biochim Biophys Acta 1832, 1473-81 (2013).
Cell cycle arrest in Batten disease lymphoblast cells.
Kang S, et al. Gene 519, 245-50 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CDI (pfam02234)
  Cyclin-dependent kinase inhibitor.
CDI (pfam02234)
  Cyclin-dependent kinase inhibitor.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cdkn1a includes H.sapiens CDKN1A and R.norvegicus Cdkn1a.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (13 transcripts, 10 species)




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