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HomoloGene:49610. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EIF5,  H.sapiens
eukaryotic translation initiation factor 5
NP_892116.2
431 aa
EIF5,  P.troglodytes
eukaryotic translation initiation factor 5
XP_001136120.1
431 aa
LOC697538,  M.mulatta
eukaryotic translation initiation factor 5-like
XP_001086107.2
444 aa
EIF5,  C.lupus
eukaryotic translation initiation factor 5
XP_868610.1
430 aa
EIF5,  B.taurus
eukaryotic translation initiation factor 5
NP_001180152.1
429 aa
Eif5,  M.musculus
eukaryotic translation initiation factor 5
NP_829887.1
429 aa
Eif5,  R.norvegicus
eukaryotic translation initiation factor 5
NP_064460.1
429 aa
EIF5,  G.gallus
eukaryotic translation initiation factor 5
NP_001006488.1
430 aa
eif5,  X.tropicalis
eukaryotic translation initiation factor 5
NP_001008209.1
431 aa
eif5,  D.rerio
eukaryotic translation initiation factor 5
NP_955885.1
429 aa
eIF5,  D.melanogaster
eIF5
NP_996480.1
464 aa
AgaP_AGAP011203,  A.gambiae
AgaP_AGAP011203
XP_309438.2
460 aa
C37C3.2,  C.elegans
C37C3.2
NP_505024.2
413 aa
TIF5,  S.cerevisiae
TIF5
NP_015366.1
405 aa
KLLA0E06095g,  K.lactis
KLLA0E06095g
XP_454221.1
398 aa
AGOS_AER400C,  E.gossypii
AGOS_AER400C
NP_985255.2
401 aa
SPAC2F7.05c,  S.pombe
SPAC2F7.05c
NP_592976.1
395 aa
MGG_08866,  M.oryzae
MGG_08866
XP_003713892.1
430 aa
NCU00366,  N.crassa
NCU00366
XP_957252.2
389 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Molecular cloning and expression of cDNA for mammalian translation initiation factor 5.
Das K, et al. Proc Natl Acad Sci U S A 90, 3058-62 (1993).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
eIF-5_eIF-2B (pfam01873)
  Domain found in IF2B/IF5.
W2 (cl17013)
  C-terminal domain of eIF4-gamma/eIF5/eIF2b-epsilon.
eIF-5_eIF-2B (cl17014)
  Domain found in IF2B/IF5.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Eif5 includes H.sapiens EIF5 and R.norvegicus Eif5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (28 transcripts, 17 species)
Actinopterygii - bony fishes (21 transcripts, 10 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Aves - birds (3 transcripts, 3 species)
Amniota - vertebrates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 12 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Coniferopsida - conifers (3 transcripts, 2 species)
Liliopsida - monocots (2 transcripts, 2 species)
Eudicotyledons - eudicots (1 transcript, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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