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HomoloGene:10313. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SULF2,  H.sapiens
sulfatase 2
NP_001155313.1
870 aa
SULF2,  P.troglodytes
sulfatase 2
XP_514701.4
552 aa
SULF2,  M.mulatta
sulfatase 2
XP_001106412.2
948 aa
SULF2,  C.lupus
sulfatase 2
NP_001041555.1
869 aa
SULF2,  B.taurus
sulfatase 2
NP_001179867.1
862 aa
Sulf2,  M.musculus
sulfatase 2
NP_001239508.1
908 aa
Sulf2,  R.norvegicus
sulfatase 2
NP_001030099.1
875 aa
SULF2,  G.gallus
sulfatase 2
XP_004947107.1
877 aa
sulf2,  X.tropicalis
sulfatase 2
NP_001005661.1
875 aa
sulf2b,  D.rerio
sulfatase 2b
NP_001003833.2
885 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Overexpression of Sulf2 in idiopathic pulmonary fibrosis.
Yue X, et al. Glycobiology 23, 709-19 (2013).
Sulf-2, a heparan sulfate endosulfatase, promotes human lung carcinogenesis.
Lemjabbar-Alaoui H, et al. Oncogene 29, 635-46 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF3740 (pfam12548)
  Sulfatase protein.
DUF3740 (pfam12548)
  Sulfatase protein.
Sulfatase (cl19157)
  Sulfatase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sulf2 includes H.sapiens SULF2 and R.norvegicus Sulf2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 14 species)
Actinopterygii - bony fishes (14 transcripts, 7 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Arthropoda
Malacostraca - crustaceans (1 transcript, 1 species)

 

 

 

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