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HomoloGene:22431. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DHH,  H.sapiens
desert hedgehog
NP_066382.1
396 aa
DHH,  C.lupus
desert hedgehog
XP_003640009.1
391 aa
DHH,  B.taurus
desert hedgehog
XP_002687352.1
396 aa
Dhh,  M.musculus
desert hedgehog
NP_031883.1
396 aa
Dhh,  R.norvegicus
desert hedgehog
NP_445819.1
396 aa
dhh,  X.tropicalis
desert hedgehog
NP_001090638.1
396 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Gonadal dysgenesis, 46XY, partial, with minifascicular neuropathy.



Publications
Articles associated with genes and sequences of this homology group.

Tissue-derived hedgehog proteins modulate Th differentiation and disease.
Furmanski AL, et al. J Immunol 190, 2641-9 (2013).
Hedgehog signalling promotes germ cell survival in the rat testis.
Mäkelä JA, et al. Reproduction 142, 711-21 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HH_signal (pfam01085)
  Hedgehog amino-terminal signalling domain.
Hint (pfam01079)
  Hint module.
Hint (pfam01079)
  Hint module.
HH_signal (pfam01085)
  Hedgehog amino-terminal signalling domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dhh includes H.sapiens DHH and R.norvegicus Dhh.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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