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HomoloGene:21247. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SERPINE2,  H.sapiens
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_001130002.1
409 aa
SERPINE2,  P.troglodytes
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
XP_001167141.2
409 aa
SERPINE2,  M.mulatta
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
XP_001109037.2
409 aa
SERPINE2,  C.lupus
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
XP_005640777.1
410 aa
SERPINE2,  B.taurus
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_777094.1
397 aa
Serpine2,  M.musculus
serine (or cysteine) peptidase inhibitor, clade E, member 2
NP_033281.1
397 aa
Serpine2,  R.norvegicus
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_062070.1
397 aa
SERPINE2,  G.gallus
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_001077389.1
442 aa
serpine2,  X.tropicalis
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_988931.2
395 aa
serpine2,  D.rerio
serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
NP_956478.1
395 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

SERPINE2 haplotype as a risk factor for panlobular type of emphysema.
Kukkonen MK, et al. BMC Med Genet 12, 157 (2011).
Association of SERPINE2 with asthma.
Himes BE, et al. Chest 140, 667-674 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SERPIN (cl00137)
  SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Serpine2 includes H.sapiens SERPINE2 and R.norvegicus Serpine2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 15 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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