Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:75070. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

INO80,  H.sapiens
INO80 complex subunit
NP_060023.1
1556 aa
INO80,  P.troglodytes
INO80 homolog (S. cerevisiae)
XP_510320.2
1556 aa
INO80,  M.mulatta
INO80 homolog (S. cerevisiae)
XP_002804786.1
1478 aa
INO80,  C.lupus
INO80 complex subunit
XP_005638316.1
1559 aa
INO80,  B.taurus
INO80 homolog (S. cerevisiae)
NP_001192313.1
1566 aa
Ino80,  M.musculus
INO80 homolog (S. cerevisiae)
NP_080850.2
1559 aa
Ino80,  R.norvegicus
INO80 complex subunit
NP_001248333.1
1559 aa
INO80,  G.gallus
INO80 homolog (S. cerevisiae)
NP_001186586.1
1560 aa
ino80,  X.tropicalis
INO80 complex subunit
XP_004917366.1
1547 aa
ino80,  D.rerio
INO80 homolog (S. cerevisiae)
NP_001038584.1
1552 aa
Ino80,  D.melanogaster
Ino80
NP_732413.1
1638 aa
AgaP_AGAP005035,  A.gambiae
AgaP_AGAP005035
XP_313902.4
1608 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair.
Chambers AL & Downs JA. Prog Mol Biol Transl Sci 110, 229-61 (2012).
Phosphorylation of human INO80 is involved in DNA damage tolerance.
Kato D, et al. Biochem Biophys Res Commun 417, 433-8 (2012).
INO80 meets a fork in the road.
Trujillo KM & Osley MA. Nat Struct Mol Biol 15, 332-4 (2008).
The Ino80 chromatin-remodeling enzyme regulates replisome function and stability.
Papamichos-Chronakis M & Peterson CL. Nat Struct Mol Biol 15, 338-45 (2008).
ATP-dependent nucleosome remodeling.
Becker PB & Hörz W. Annu Rev Biochem 71, 247-73 (2002).
The potential role of ubiquitin c-terminal hydrolases in oncogenesis.
Fang Y, et al. Biochim Biophys Acta 1806, 1-6 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DBINO (pfam13892)
  DNA-binding domain.
HELICc (cd00079)
  Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
DUF1682 (pfam07946)
  Protein of unknown function (DUF1682).
DBINO (pfam13892)
  DNA-binding domain.
DEXDc (cl17251)
  DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ino80 includes H.sapiens INO80 and R.norvegicus Ino80.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 9 species)
Actinopterygii - bony fishes (13 transcripts, 8 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 6 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (8 transcripts, 7 species)
Liliopsida - monocots (6 transcripts, 5 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (2 transcripts, 1 species)

 

 

 

Support Center