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HomoloGene:56279. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RECQL,  H.sapiens
RecQ helicase-like
NP_002898.2
649 aa
RECQL,  P.troglodytes
RecQ protein-like (DNA helicase Q1-like)
XP_520788.3
649 aa
RECQL,  M.mulatta
RecQ protein-like (DNA helicase Q1-like)
XP_002798535.1
649 aa
RECQL,  C.lupus
RecQ protein-like (DNA helicase Q1-like)
XP_543768.1
646 aa
RECQL,  B.taurus
RecQ protein-like (DNA helicase Q1-like)
NP_001071459.1
649 aa
Recql,  M.musculus
RecQ protein-like
NP_075529.2
648 aa
Recql,  R.norvegicus
RecQ protein-like (DNA helicase Q1-like)
NP_001012098.1
621 aa
RECQL,  G.gallus
RecQ protein-like (DNA helicase Q1-like)
NP_989724.1
661 aa
recql,  X.tropicalis
RecQ protein-like (DNA helicase Q1-like)
NP_001016316.1
558 aa
recql,  D.rerio
RecQ protein-like (DNA helicase Q1-like)
NP_001038561.2
639 aa
K02F3.12,  C.elegans
K02F3.12
NP_001022656.1
631 aa
MGG_05700,  M.oryzae
MGG_05700
XP_003710599.1
1780 aa
RECQL2,  A.thaliana
RECQL2
NP_174421.2
705 aa
Os11g0708600,  O.sativa
Os11g0708600
NP_001068564.1
685 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Structure of the human RECQ1 helicase reveals a putative strand-separation pin.
Pike AC, et al. Proc Natl Acad Sci U S A 106, 1039-44 (2009).
RECQ1 possesses DNA branch migration activity.
Bugreev DV, et al. J Biol Chem 283, 20231-42 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HRDC (cl02578)
  HRDC domain.
RQC (pfam09382)
  RQC domain.
HELICc (cd00079)
  Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
RQC (cl09632)
  RQC domain.
HRDC (cl02578)
  HRDC domain.
RQC (cl09632)
  RQC domain.
DEXDc (cl17251)
  DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Recql includes H.sapiens RECQL and R.norvegicus Recql.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 12 species)
Actinopterygii - bony fishes (14 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (7 transcripts, 6 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (14 transcripts, 12 species)
Liliopsida - monocots (4 transcripts, 4 species)
Coniferopsida - conifers (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (3 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)

 

 

 

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