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HomoloGene:3251. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RCAN1,  H.sapiens
regulator of calcineurin 1
NP_004405.3
252 aa
RCAN1,  P.troglodytes
regulator of calcineurin 1
NP_001092027.1
117 aa
RCAN1,  M.mulatta
regulator of calcineurin 1
XP_001088613.1
249 aa
RCAN1,  C.lupus
regulator of calcineurin 1
XP_849295.1
249 aa
Rcan1,  M.musculus
regulator of calcineurin 1
NP_001075018.1
251 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Upregulation of RCAN1 causes Down syndrome-like immune dysfunction.
Martin KR, et al. J Med Genet 50, 444-54 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Calcipressin (pfam04847)
  Calcipressin.
RRM_SF (cl17169)
  RNA recognition motif (RRM) superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rcan1 includes H.sapiens RCAN1 and R.norvegicus Rcan1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (9 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

 

 

 

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