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HomoloGene:32531. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EGLN3,  H.sapiens
egl-9 family hypoxia-inducible factor 3
NP_071356.1
239 aa
EGLN3,  P.troglodytes
egl nine homolog 3 (C. elegans)
XP_509896.3
239 aa
EGLN3,  M.mulatta
egl nine homolog 3 (C. elegans)
XP_002805061.1
239 aa
EGLN3,  C.lupus
egl-9 family hypoxia-inducible factor 3
XP_537408.3
239 aa
EGLN3,  B.taurus
egl nine homolog 3 (C. elegans)
NP_001094634.1
239 aa
Egln3,  M.musculus
EGL nine homolog 3 (C. elegans)
NP_082409.2
239 aa
Egln3,  R.norvegicus
egl-9 family hypoxia-inducible factor 3
NP_062244.1
355 aa
EGLN3,  G.gallus
egl nine homolog 3 (C. elegans)
XP_421233.3
241 aa
egln3,  X.tropicalis
egl-9 family hypoxia-inducible factor 3
NP_001120484.1
252 aa
egln3,  D.rerio
egl nine homolog 3 (C. elegans)
NP_998475.1
236 aa
AgaP_AGAP003523,  A.gambiae
AgaP_AGAP003523
XP_313264.5
741 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.
Rantanen K, et al. Mol Biol Cell 19, 2231-40 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-MYND (pfam01753)
  MYND finger.
2OG-FeII_Oxy_3 (cl17304)
  2OG-Fe(II) oxygenase superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Egln3 includes H.sapiens EGLN3 and R.norvegicus Egln3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (11 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 4 species)
Arachnida - arachnids (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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