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HomoloGene:68380. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FKBP1B,  H.sapiens
FK506 binding protein 1B, 12.6 kDa
NP_004107.1
108 aa
FKBP1B,  P.troglodytes
FK506 binding protein 1B, 12.6 kDa
XP_001144201.2
108 aa
FKBP1B,  M.mulatta
FK506 binding protein 1B, 12.6 kDa
XP_001098297.1
108 aa
FKBP1B,  C.lupus
FK506 binding protein 1B, 12.6 kDa
XP_853461.1
108 aa
FKBP1B,  B.taurus
FK506 binding protein 1B, 12.6 kDa
NP_001091627.1
108 aa
Fkbp1b,  M.musculus
FK506 binding protein 1b
NP_058559.3
108 aa
Fkbp1b,  R.norvegicus
FK506 binding protein 1B
NP_073166.1
108 aa
FKBP1B,  G.gallus
FK506 binding protein 1B, 12.6 kDa
NP_989898.1
108 aa
fkbp1b,  X.tropicalis
FK506 binding protein 1B, 12.6 kDa
NP_001096492.1
108 aa
fkbp1b,  D.rerio
FK506 binding protein 1b
NP_957106.1
108 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

FKBP12.6 disruption impairs glucose-induced insulin secretion.
Noguchi N, et al. Biochem Biophys Res Commun 371, 735-40 (2008).
Structure of FKBP12.6 in complex with rapamycin.
Deivanayagam CC, et al. Acta Crystallogr D Biol Crystallogr 56, 266-71 (2000).
Inhibition of calcineurin by a novel FK-506-binding protein.
Sewell TJ, et al. J Biol Chem 269, 21094-102 (1994).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FKBP_C (pfam00254)
  FKBP-type peptidyl-prolyl cis-trans isomerase.
FKBP_C (cl19519)
  FKBP-type peptidyl-prolyl cis-trans isomerase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fkbp1b includes H.sapiens FKBP1B and R.norvegicus Fkbp1b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (11 transcripts, 10 species)
Amphibia - amphibians (7 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

 

 

 

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