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HomoloGene:20696. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TLR3,  H.sapiens
toll-like receptor 3
NP_003256.1
904 aa
TLR3,  P.troglodytes
toll-like receptor 3
NP_001123942.1
904 aa
TLR3,  M.mulatta
toll-like receptor 3
NP_001031762.1
904 aa
TLR3,  C.lupus
toll-like receptor 3
XP_005630025.1
905 aa
TLR3,  B.taurus
toll-like receptor 3
NP_001008664.1
904 aa
Tlr3,  M.musculus
toll-like receptor 3
NP_569054.2
905 aa
Tlr3,  R.norvegicus
toll-like receptor 3
NP_942086.1
905 aa
TLR3,  G.gallus
toll-like receptor 3
NP_001011691.3
896 aa
tlr3,  X.tropicalis
toll-like receptor 3
XP_002934448.2
895 aa
tlr3,  D.rerio
toll-like receptor 3
NP_001013287.2
903 aa
Tollo,  D.melanogaster
Tollo
NP_524757.1
1346 aa
AgaP_AGAP012385,  A.gambiae
AgaP_AGAP012385
XP_551799.2
1353 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Herpes simplex encephalitis, TLR3-deficient, susceptibility to.
Geographic atrophy, susceptibility to progression to, in age-related macular degeneration.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_5 (pfam13306)
  Leucine rich repeats (6 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl15770)
  TIR domain.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
TIR (pfam01582)
  TIR domain.
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl17458)
  TIR domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tlr3 includes H.sapiens TLR3 and R.norvegicus Tlr3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 12 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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