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HomoloGene:21137. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MNX1,  H.sapiens
motor neuron and pancreas homeobox 1
NP_005506.3
401 aa
MNX1,  P.troglodytes
motor neuron and pancreas homeobox 1
XP_001150658.2
398 aa
LOC722832,  M.mulatta
motor neuron and pancreas homeobox protein 1-like
XP_001118925.1
117 aa
MNX1,  C.lupus
motor neuron and pancreas homeobox 1
XP_539936.2
319 aa
MNX1,  B.taurus
motor neuron and pancreas homeobox 1
XP_002687033.2
180 aa
Mnx1,  M.musculus
motor neuron and pancreas homeobox 1
NP_064328.2
404 aa
Mnx1,  R.norvegicus
motor neuron and pancreas homeobox 1
NP_001258203.1
403 aa
MNX1,  G.gallus
motor neuron and pancreas homeobox 1
NP_990259.1
349 aa
mnx1,  X.tropicalis
motor neuron and pancreas homeobox 1
XP_002935225.1
339 aa
mnx1,  D.rerio
motor neuron and pancreas homeobox 1
NP_001009885.1
311 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Currarino syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Rodent models of amyotrophic lateral sclerosis.
McGoldrick P, et al. Biochim Biophys Acta 1832, 1421-36 (2013).
A novel HLXB9 mutation in a Chinese family with Currarino syndrome.
Wang Y & Wu Y. Eur J Pediatr Surg 22, 243-5 (2012).
The dual role of HLXB9 in leukemia.
Ferguson S, et al. Pediatr Blood Cancer 56, 349-52 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mnx1 includes H.sapiens MNX1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (3 transcripts, 3 species)
Mammalia - mammals (2 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 3 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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