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HomoloGene:16811. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CROCC,  H.sapiens
ciliary rootlet coiled-coil, rootletin
NP_055490.3
2017 aa
CROCC,  P.troglodytes
ciliary rootlet coiled-coil, rootletin
XP_513109.2
2017 aa
CROCC,  C.lupus
ciliary rootlet coiled-coil, rootletin
XP_544542.4
2019 aa
CROCC,  B.taurus
ciliary rootlet coiled-coil, rootletin
XP_002685844.2
1984 aa
Crocc,  M.musculus
ciliary rootlet coiled-coil, rootletin
NP_742120.2
2009 aa
Crocc,  R.norvegicus
ciliary rootlet coiled-coil, rootletin
NP_001101460.2
1846 aa
CROCC,  G.gallus
ciliary rootlet coiled-coil, rootletin
XP_425750.4
1726 aa
LOC100498193,  X.tropicalis
rootletin-like
XP_002933382.2
2027 aa
LOC101885282,  D.rerio
rootletin-like
XP_005166013.1
1857 aa
Rootletin,  D.melanogaster
Rootletin
NP_651216.2
2048 aa
AgaP_AGAP003449,  A.gambiae
AgaP_AGAP003449
XP_311738.5
2116 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The ciliary rootlet maintains long-term stability of sensory cilia.
Yang J, et al. Mol Cell Biol 25, 4129-37 (2005).
beta-Catenin is a Nek2 substrate involved in centrosome separation.
Bahmanyar S, et al. Genes Dev 22, 91-105 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
SMC_prok_A (TIGR02169)
  chromosome segregation protein SMC, primarily archaeal type.
Rootletin (pfam15035)
  Ciliary rootlet component, centrosome cohesion.
DUF342 (cl19219)
  Protein of unknown function (DUF342).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Crocc includes H.sapiens CROCC and R.norvegicus Crocc.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (5 transcripts, 2 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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