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HomoloGene:3123. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

KLF4,  H.sapiens
Kruppel-like factor 4 (gut)
NP_004226.3
479 aa
KLF4,  P.troglodytes
Kruppel-like factor 4 (gut)
XP_001141754.1
479 aa
KLF4,  M.mulatta
Kruppel-like factor 4 (gut)
NP_001136265.1
479 aa
KLF4,  C.lupus
Kruppel-like factor 4 (gut)
XP_005627053.1
450 aa
KLF4,  B.taurus
Kruppel-like factor 4 (gut)
NP_001098855.1
477 aa
Klf4,  M.musculus
Kruppel-like factor 4 (gut)
NP_034767.2
483 aa
Klf4,  R.norvegicus
Kruppel-like factor 4 (gut)
NP_446165.1
482 aa
KLF4,  G.gallus
Kruppel-like factor 4 (gut)
XP_004949426.1
458 aa
klf4,  X.tropicalis
Kruppel-like factor 4 (gut)
NP_001017280.1
407 aa
klf4a,  D.rerio
Kruppel-like factor 4a
NP_001106955.1
396 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

KLF4 expression and apoptosis-related markers in gastric cancer.
Krstic M, et al. J BUON 18, 695-702 (2013).
Localization and function of KLF4 in cytoplasm of vascular smooth muscle cell.
Liu Y, et al. Biochem Biophys Res Commun 436, 162-8 (2013).
Myeloid Krüppel-like factor 4 deficiency augments atherogenesis in ApoE-/- mice--brief report.
Sharma N, et al. Arterioscler Thromb Vasc Biol 32, 2836-8 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ZnF_C2H2 (smart00355)
  zinc finger.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Klf4 includes H.sapiens KLF4 and R.norvegicus Klf4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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