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HomoloGene:1132. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GABBR1,  H.sapiens
gamma-aminobutyric acid (GABA) B receptor, 1
NP_001461.1
961 aa
GABBR1,  P.troglodytes
gamma-aminobutyric acid (GABA) B receptor, 1
XP_527324.4
819 aa
GABBR1,  M.mulatta
gamma-aminobutyric acid (GABA) B receptor, 1
XP_001097474.2
844 aa
GABBR1,  C.lupus
gamma-aminobutyric acid (GABA) B receptor, 1
XP_005640226.1
787 aa
GABBR1,  B.taurus
gamma-aminobutyric acid (GABA) B receptor, 1
NP_001156747.1
961 aa
Gabbr1,  M.musculus
gamma-aminobutyric acid (GABA) B receptor, 1
NP_062312.3
960 aa
Gabbr1,  R.norvegicus
gamma-aminobutyric acid (GABA) B receptor 1
NP_112290.2
960 aa
gabbr1,  X.tropicalis
gamma-aminobutyric acid (GABA) B receptor, 1
NP_001107291.1
924 aa
gabbr1a,  D.rerio
gamma-aminobutyric acid (GABA) B receptor, 1a
XP_694497.5
988 aa
gabbr1b,  D.rerio
gamma-aminobutyric acid (GABA) B receptor, 1b
XP_005170159.1
994 aa
GABA-B-R1,  D.melanogaster
metabotropic GABA-B receptor subtype 1
NP_001246033.1
841 aa
GPRGBB1,  A.gambiae
GPRGBB1
XP_319474.3
764 aa
gbb-1,  C.elegans
gbb-1
NP_741740.2
868 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

GABA(B) autoreceptor-mediated cell type-specific reduction of inhibition in epileptic mice.
Dugladze T, et al. Proc Natl Acad Sci U S A 110, 15073-8 (2013).
Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors.
Crivello M, et al. Am J Physiol Endocrinol Metab 304, E1064-76 (2013).
Sex differences in insulin resistance in GABAB1 knockout mice.
Bonaventura MM, et al. Life Sci 92, 175-82 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_3 (pfam00003)
  7 transmembrane sweet-taste receptor of 3 GCPR.
7tm_3 (pfam00003)
  7 transmembrane sweet-taste receptor of 3 GCPR.
Plant_vir_prot (pfam01307)
  Plant viral movement protein.
THOC7 (pfam05615)
  Tho complex subunit 7.
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
Periplasmic_Binding_Protein_Type_1 (cl10011)
  Type 1 periplasmic binding fold superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gabbr1 includes H.sapiens GABBR1 and R.norvegicus Gabbr1.

 

 

 

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