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HomoloGene:52819. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC6A19,  H.sapiens
solute carrier family 6 (neutral amino acid transporter), member 19
NP_001003841.1
634 aa
SLC6A19,  P.troglodytes
solute carrier family 6 (neutral amino acid transporter), member 19
XP_003950546.1
587 aa
SLC6A19,  M.mulatta
solute carrier family 6 (neutral amino acid transporter), member 19
XP_002804345.1
622 aa
SLC6A19,  C.lupus
solute carrier family 6 (neutral amino acid transporter), member 19
XP_003434149.1
634 aa
SLC6A19,  B.taurus
solute carrier family 6 (neutral amino acid transporter), member 19
XP_002696512.2
656 aa
Slc6a19,  M.musculus
solute carrier family 6 (neurotransmitter transporter), member 19
NP_083154.1
634 aa
Slc6a19,  R.norvegicus
solute carrier family 6 (neutral amino acid transporter), member 19
NP_001034811.1
634 aa
SLC6A19,  G.gallus
solute carrier family 6 (neutral amino acid transporter), member 19
XP_419056.1
636 aa
slc6a19,  X.tropicalis
solute carrier family 6 (neutral amino acid transporter), member 19
NP_001120585.1
636 aa
slc6a19a,  D.rerio
solute carrier family 6 (neurotransmitter transporter), member 19a
NP_001091648.1
629 aa
LOC100334171,  D.rerio
sodium-dependent neutral amino acid transporter B(0)AT1-like
XP_002665492.2
647 aa
slc6a19b,  D.rerio
solute carrier family 6 (neurotransmitter transporter), member 19b
NP_956030.1
651 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hartnup disorder.



Publications
Articles associated with genes and sequences of this homology group.

Novel mutation in SLC6A19 causing late-onset seizures in Hartnup disorder.
Cheon CK, et al. Pediatr Neurol 42, 369-71 (2010).
Roux-en-Y gastric bypass alters small intestine glutamine transport in the obese Zucker rat.
Wolff BS, et al. Am J Physiol Gastrointest Liver Physiol 297, G594-601 (2009).
Minisatellite polymorphisms of the SLC6A19: susceptibility in hypertension.
Seol SY, et al. Biochem Biophys Res Commun 374, 714-9 (2008).
Further evidence for allelic heterogeneity in Hartnup disorder.
Azmanov DN, et al. Hum Mutat 29, 1217-21 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SLC5-6-like_sbd (cl00456)
  Solute carrier families 5 and 6-like; solute binding domain.
SLC5-6-like_sbd (cl00456)
  Solute carrier families 5 and 6-like; solute binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc6a19 includes H.sapiens SLC6A19 and R.norvegicus Slc6a19.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (18 transcripts, 8 species)
Mammalia - mammals (13 transcripts, 10 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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